Research has shown PEMF therapy exerts its healing effects on the body through various cellular, molecular, and physiological mechanisms such as:
Cellular Effects: Research indicates PEMF therapy influences a number of cellular processes, such as promoting the production of ATP (adenosine triphosphate) the primary energy source for cells. Increased ATP production can enhance cellular metabolism and function, thereby improving tissue repair and regeneration.
Calcium Ion Movement: PEMF therapy is believed to affect movement of calcium ions within cells and tissues. Calcium ions play an important role in the pathways involved in tissue repair and bone remodeling.
Gene Expression: PEMF therapy has been shown to influence gene expression, specifically those related to tissue repair and regeneration thereby promoting the synthesis of key proteins necessary in healing processes.
Anti-inflammatory Effects: Research indicates PEMF therapy reduces the production of pro-inflammatory cytokines, while increasing the release of anti-inflammatory mediators. Reducing inflammation is know to enhance tissue healing.
Angiogenesis: PEMF therapy has been shown to stimulate the formation of new blood vessels (angiogenesis). These new vessels allow for increased blood flow to damaged tissues. Increased blood flow enhances the delivery of oxygen and nutrients to the area which in turn contributes to faster tissue repair and regeneration.
Bone Remodeling: Research has shown PEMF therapy increases osteoblast activity (cells responsible for bone formation) while inhibiting osteoclast activity (cells responsible for bone resorption).
In this way, PEMF therapy supports the process of bone remodeling and fracture healing.